Inhibition of glutathione efflux in the perfused rat liver and isolated hepatocytes by organic anions and bilirubin. Kinetics, sidedness, and molecular forms.

Using isolated, in situ, single-pass perfused rat livers, incubations of freshly isolated hepatocytes, and sinusoidal membrane-enriched vesicles, we and others have shown the saturability of transport (efflux) of hepatic glutathione (GSH). These observations have implicated a carrier mechanism. Our...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Ookhtens, M, Lyon, I, Fernandez-Checa, J, Kaplowitz, N
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1988
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303555/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3403719/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113639
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