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Western diet changes cardiac acyl-CoA composition in obese rats: a potential role for hepatic lipogenesis

The “lipotoxic footprint” of cardiac maladaptation in diet-induced obesity is poorly defined. We investigated how manipulation of dietary lipid and carbohydrate influenced potential lipotoxic species in the failing heart. In Wistar rats, contractile dysfunction develops at 48 weeks on a high-fat/hig...

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Bibliografische gegevens
Hoofdauteurs: Harmancey, Romain, Wilson, Christopher R., Wright, Nathan R., Taegtmeyer, Heinrich
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035501/
https://ncbi.nlm.nih.gov/pubmed/20093477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M001230
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