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End-processing during non-homologous end-joining: a role for exonuclease 1

Non-homologous end-joining (NHEJ) is a critical error-prone pathway of double strand break repair. We recently showed that tyrosyl DNA phosphodiesterase 1 (Tdp1) regulates the accuracy of NHEJ repair junction formation in yeast. We assessed the role of other enzymes in the accuracy of junction forma...

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Bibliografske podrobnosti
Main Authors: Bahmed, Karim, Seth, Aman, Nitiss, Karin C., Nitiss, John L.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035470/
https://ncbi.nlm.nih.gov/pubmed/20935051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq886
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