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Cleavage of model substrates by archaeal RNase P: role of protein cofactors in cleavage-site selection

RNase P is a catalytic ribonucleoprotein primarily involved in tRNA biogenesis. Archaeal RNase P comprises a catalytic RNase P RNA (RPR) and at least four protein cofactors (RPPs), which function as two binary complexes (POP5•RPP30 and RPP21• RPP29). Exploiting the ability to assemble a functional P...

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Bibliografische gegevens
Hoofdauteurs: Sinapah, Sylvie, Wu, Shiying, Chen, Yu, Pettersson, B. M. Fredrik, Gopalan, Venkat, Kirsebom, Leif A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2011
Onderwerpen:
RNA
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035440/
https://ncbi.nlm.nih.gov/pubmed/20935047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq732
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