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SIRT6: A master epigenetic gatekeeper of glucose metabolism

Sirtuins are the mammalian homologs of the yeast histone deacetylase Sir2. In recent years, an ever-expanding picture has emerged indicating that these proteins (SIRT1-7) play broad functions in cellular stress resistance, genomic stability, energy metabolism, aging and tumorigenesis.1 Among members...

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Hlavní autoři: Zhong, Lei, Mostoslavsky, Raul
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035182/
https://ncbi.nlm.nih.gov/pubmed/21327158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.1.1.12143
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