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Discovery of Antagonist Peptides against Bacterial Helicase-Primase Interaction in B. stearothermophilus by Reverse Yeast Three-Hybrid

Developing small-molecule antagonists against protein-protein interactions will provide powerful tools for mechanistic/functional studies and the discovery of new antibacterials. We have developed a reverse yeast three-hybrid approach that allows high-throughput screening for antagonist peptides aga...

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Detalhes bibliográficos
Main Authors: Gardiner, Laurence, Coyle, Barry J., Chan, Weng C., Soultanas, Panos
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035177/
https://ncbi.nlm.nih.gov/pubmed/15911380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2005.04.007
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