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Nodes of Ranvier Act as Barriers to Restrict Invasion of Flanking Paranodal Domains in Myelinated Axons

Accumulation of voltage gated sodium (Na(v)) channels at nodes of Ranvier is paramount for action potential propagation along myelinated fibers, yet the mechanisms governing nodal development, organization and stabilization remain unresolved. Here, we report that genetic ablation of the neuron-speci...

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Bibliographic Details
Main Authors: Thaxton, Courtney, Pillai, Anilkumar M., Pribisko, Alaine L., Dupree, Jeffrey L., Bhat, Manzoor A.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035172/
https://ncbi.nlm.nih.gov/pubmed/21262464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.12.016
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