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Nodes of Ranvier Act as Barriers to Restrict Invasion of Flanking Paranodal Domains in Myelinated Axons

Accumulation of voltage gated sodium (Na(v)) channels at nodes of Ranvier is paramount for action potential propagation along myelinated fibers, yet the mechanisms governing nodal development, organization and stabilization remain unresolved. Here, we report that genetic ablation of the neuron-speci...

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Detalhes bibliográficos
Main Authors: Thaxton, Courtney, Pillai, Anilkumar M., Pribisko, Alaine L., Dupree, Jeffrey L., Bhat, Manzoor A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035172/
https://ncbi.nlm.nih.gov/pubmed/21262464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.12.016
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