Spatiotemporal Ablation of Myelinating Glia-Specific Neurofascin (Nfasc(NF155)) in Mice Reveals Gradual Loss of Paranodal Axoglial Junctions and Concomitant Disorganization of Axonal Domains

The evolutionary demand for rapid nerve impulse conduction led to the process of myelination-dependent organization of axons into distinct molecular domains. These domains include the node of Ranvier flanked by highly specialized paranodal domains where myelin loops and axolemma orchestrate the axog...

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Bibliographic Details
Main Authors: Pillai, Anilkumar M., Thaxton, Courtney, Pribisko, Alaine L., Cheng, Jr-Gang, Dupree, Jeffrey L., Bhat, Manzoor A.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837286/
https://ncbi.nlm.nih.gov/pubmed/19185024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22015
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