Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro.

The effect of insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was studied. Western blot analysis of whole cell lysates of cell lines NCI-H345 and NCI-N417 demonstrated the presence of a 16-kD band consistent with an IGF-I precursor molecule. Scatchard plot...

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Detalhes bibliográficos
Main Authors: Nakanishi, Y, Mulshine, J L, Kasprzyk, P G, Natale, R B, Maneckjee, R, Avis, I, Treston, A M, Gazdar, A F, Minna, J D, Cuttitta, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303516/
https://ncbi.nlm.nih.gov/pubmed/2839551
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