Opioid and nicotine receptors affect growth regulation of human lung cancer cell lines.
Using specific ligands, we find that lung cancer cell lines of diverse histologic types express multiple, high-affinity (Kd = 10(-9)-10(-10) M) membrane receptors for mu, delta, and kappa opioid agonists and for nicotine and alpha-bungarotoxin. These receptors are biologically active because cAMP le...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2159143/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.9.3294 |
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