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How microchimerism can impart HLA susceptibility in patients with rheumatoid arthritis
Rheumatoid arthritis, a chronic inflammatory joint disease, is strongly associated with HLA-DRB1*01 and *04 alleles that have in common similar 5-amino acid motifs in the third hypervariable region of DRB1 (QKRAA, QRRAA, RRRAA), the so called shared epitope (SE). Most patients with RA carry 1 or 2 d...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035110/ https://ncbi.nlm.nih.gov/pubmed/21327148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chim.1.1.12648 |
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