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How microchimerism can impart HLA susceptibility in patients with rheumatoid arthritis

Rheumatoid arthritis, a chronic inflammatory joint disease, is strongly associated with HLA-DRB1*01 and *04 alleles that have in common similar 5-amino acid motifs in the third hypervariable region of DRB1 (QKRAA, QRRAA, RRRAA), the so called shared epitope (SE). Most patients with RA carry 1 or 2 d...

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Detalhes bibliográficos
Main Authors: Azzouz, Doua F., Rak, Justyna M., Balandraud, Nathalie, Auger, Isabelle, Martin, Marielle, Roudier, Jean, Lambert, Nathalie C.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035110/
https://ncbi.nlm.nih.gov/pubmed/21327148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chim.1.1.12648
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