Cooperative activity of noggin and gremlin 1 in axial skeleton development

Inductive signals from adjacent tissues initiate differentiation within the somite. In this study, we used mouse embryos mutant for the BMP antagonists noggin (Nog) and gremlin 1 (Grem1) to characterize the effects of BMP signaling on the specification of the sclerotome. We confirmed reduction of Pa...

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Autors principals: Stafford, David A., Brunet, Lisa J., Khokha, Mustafa K., Economides, Aris N., Harland, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035099/
https://ncbi.nlm.nih.gov/pubmed/21303853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.051938
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