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Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes

Mammalian imprinted genes are associated with differentially methylated regions (DMRs) that are CpG methylated on one of the two parental chromosomes. In mice, at least 21 DMRs acquire differential methylation in the germline and many of them act as imprint centres. We previously reported the physic...

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Hlavní autoři: Tomizawa, Shin-ichi, Kobayashi, Hisato, Watanabe, Toshiaki, Andrews, Simon, Hata, Kenichiro, Kelsey, Gavin, Sasaki, Hiroyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035086/
https://ncbi.nlm.nih.gov/pubmed/21247965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.061416
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