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Pharmacogenetic effect of an endothelin-1 haplotype on response to bucindolol therapy in chronic heart failure

BACKGROUND: Beta-blocker therapy has become a mainstay therapy for the over 5 million patients with chronic heart failure in the United States. Variation in clinical response to β-blockers is a well-known phenomenon and may be because of genetic differences between patients. We hypothesized that var...

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Detalhes bibliográficos
Main Authors: Taylor, Matthew R.G., Slavov, Dobromir, Humphrey, Kurt, Zhao, Lan, Cockroft, Jennifer, Zhu, Xiao, Lavori, Philip, Bristow, Michael R., Mestroni, Luisa, Lazzeroni, Laura C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035051/
https://ncbi.nlm.nih.gov/pubmed/18953265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328317cc57
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