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Effect of small interfering RNA 3'-end overhangs on chemosensitivity to thymidylate synthase inhibitors
BACKGROUND: Small interfering RNAs (siRNAs) are double-stranded RNAs that effectively inhibit expression of its complimentary target mRNA. Standard siRNAs contain two nucleotide overhangs on their 3' end. While these overhangs are usually comprised of deoxythymidines (dT), it has been shown tha...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035029/ https://ncbi.nlm.nih.gov/pubmed/21247442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-907X-2-1 |
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