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Effect of small interfering RNA 3'-end overhangs on chemosensitivity to thymidylate synthase inhibitors
BACKGROUND: Small interfering RNAs (siRNAs) are double-stranded RNAs that effectively inhibit expression of its complimentary target mRNA. Standard siRNAs contain two nucleotide overhangs on their 3' end. While these overhangs are usually comprised of deoxythymidines (dT), it has been shown tha...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035029/ https://ncbi.nlm.nih.gov/pubmed/21247442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-907X-2-1 |
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