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Factor VIII-bypassing activity of bovine tissue factor using the canine hemophilic model.

The bleeding disorder of hemophilia A currently treated by replacement therapy of the missing coagulation factor, factor VIII, is frequently complicated by the development of neutralizing antibodies. The therapeutic potential of attenuated forms of the lipid-associated glycoprotein tissue factor, a...

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Udgivet i:J Clin Invest
Principais autores: O'Brien, D P, Giles, A R, Tate, K M, Vehar, G A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303495/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3134399/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113571
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