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Spectroscopic Characterization of Intermolecular Interaction of Amyloid β Promoted on GM1 Micelles

Clusters of GM1 gangliosides act as platforms for conformational transition of monomeric, unstructured amyloid β (Aβ) to its toxic β-structured aggregates. We have previously shown that Aβ(1–40) accommodated on the hydrophobic/hydrophilic interface of lyso-GM1 or GM1 micelles assumes α-helical struc...

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Bibliografski detalji
Glavni autori: Yagi-Utsumi, Maho, Matsuo, Koichi, Yanagisawa, Katsuhiko, Gekko, Kunihiko, Kato, Koichi
Format: Artigo
Jezik:Inglês
Izdano: SAGE-Hindawi Access to Research 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034947/
https://ncbi.nlm.nih.gov/pubmed/21318130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/925073
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