Vaccine-induced T cells Provide Partial Protection Against High-dose Rectal SIVmac239 Challenge of Rhesus Macaques

Despite enormous efforts by the scientific community, an effective HIV vaccine remains elusive. To further address to what degree T cells in absence of antibodies may protect against simian immunodeficiency virus (SIV) disease progression, rhesus macaques were vaccinated intramuscularly with a chimp...

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Detalhes bibliográficos
Main Authors: Lasaro, Marcio O, Haut, Larissa H, Zhou, Xiangyang, Xiang, Zhiquan, Zhou, Dongming, Li, Yan, Giles-Davis, Wynetta, Li, Hua, Engram, Jessica C, DiMenna, Lauren J, Bian, Ang, Sazanovich, Marina, Parzych, Elizabeth M, Kurupati, Raj, Small, Juliana C, Wu, Te-Lang, Leskowitz, Rachel M, Klatt, Nicole R, Brenchley, Jason M, Garber, David A, Lewis, Mark, Ratcliffe, Sarah J, Betts, Michael R, Silvestri, Guido, Ertl, Hildegund C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034846/
https://ncbi.nlm.nih.gov/pubmed/21081905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.238
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