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Sex-specific timing of meiotic initiation is regulated by Cyp26b1 independent of retinoic acid signalling

Sex-specific initiation of meiosis in the fetal ovary has been suggested to require retinoic acid (RA) for induction of Stra8, with expression of the RA-degrading enzyme Cyp26b1 in fetal testis delaying meiosis until postnatal development. In this study, we investigate Raldh2(−/−) mice lacking RA sy...

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Detalhes bibliográficos
Main Authors: Kumar, Sandeep, Chatzi, Christina, Brade, Thomas, Cunningham, Thomas J., Zhao, Xianling, Duester, Gregg
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034736/
https://ncbi.nlm.nih.gov/pubmed/21224842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1136
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