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Autoreactive marginal zone B cells enter the follicles and interact with CD4(+ )T cells in lupus-prone mice

BACKGOUND: Marginal zone B cells have been implicated in the production of autoantibodies in murine models of lupus. It has been suggested that they contribute to lupus immunopathogenesis through their enhanced effector functions and their repertoire that is biased toward autoreactive specificities....

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Main Authors: Zhou, Zhenhai, Niu, Haitao, Zheng, Ying-Yi, Morel, Laurence
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034709/
https://ncbi.nlm.nih.gov/pubmed/21251257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-7
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