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Autoreactive marginal zone B cells enter the follicles and interact with CD4(+ )T cells in lupus-prone mice

BACKGOUND: Marginal zone B cells have been implicated in the production of autoantibodies in murine models of lupus. It has been suggested that they contribute to lupus immunopathogenesis through their enhanced effector functions and their repertoire that is biased toward autoreactive specificities....

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Autors principals: Zhou, Zhenhai, Niu, Haitao, Zheng, Ying-Yi, Morel, Laurence
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034709/
https://ncbi.nlm.nih.gov/pubmed/21251257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-7
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