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Crystallization and preliminary X-ray analysis of the human long myosin light-chain kinase 1-specific domain IgCAM3

Myosin light-chain kinase-dependent tight junction regulation is a critical event in inflammatory cytokine-induced increases in epithelial paracellular permeability. MLCK is expressed in human intestinal epithelium as two isoforms, long MLCK1 and long MLCK2, and MLCK1 is specifically localized to th...

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Main Authors: Graham, W. Vallen, Magis, Andrew T., Bailey, Kate M., Turner, Jerrold R., Ostrov, David A.
格式: Artigo
語言:Inglês
出版: International Union of Crystallography 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034612/
https://ncbi.nlm.nih.gov/pubmed/21301090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110050323
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