Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells

Long INterspersed Element-1 (LINE-1 or L1) retrotransposition continues to impact human genome evolution1,2. L1s can retrotranspose in the germline, during early development, and in select somatic cells3,4,5,6,7,8; however, the host response to L1 retrotransposition remains largely unexplored. Here,...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Garcia-Perez, Jose L., Morell, Maria, Scheys, Joshua O., Kulpa, Deanna A., Morell, Santiago, Carter, Christoph C., Hammer, Gary D., Collins, Kathleen L., O’Shea, K. Sue, Menendez, Pablo, Moran, John V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034402/
https://ncbi.nlm.nih.gov/pubmed/20686575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09209
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi