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Ciproxifan, an H(3) Receptor Antagonist, Alleviates Hyperactivity and Cognitive Deficits in the APP(Tg2576) Mouse Model of Alzheimer’s Disease

Previous research has indicated that the blockade of H(3)-type histamine receptors may improve attention and memory in normal rodents. The purpose of this study was to determine if ciproxifan, an H(3) receptor antagonist, could alleviate the hyperactivity and cognitive deficits observed in a transge...

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Detalhes bibliográficos
Main Authors: Bardgett, Mark E., Davis, Natasha N., Schultheis, Patrick J., Griffith, Molly S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034295/
https://ncbi.nlm.nih.gov/pubmed/21073971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2010.10.008
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