Effects of mineralocorticoid receptor blockade on glucocorticoid-induced renal injury in adrenalectomized rats

OBJECTIVES: Aldosterone is well recognized as the selective physiological ligand for mineralocorticoid receptor in epithelia. However, in-vitro studies have demonstrated that the affinity of aldosterone and glucocorticoids for mineralocorticoid receptor is similar. We hypothesized that glucocorticoi...

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Main Authors: Rafiq, Kazi, Nakano, Daisuke, Ihara, Genei, Hitomi, Hirofumi, Fujisawa, Yoshihide, Ohashi, Naro, Kobori, Hiroyuki, Nagai, Yukiko, Kiyomoto, Hideyasu, Kohno, Masakazu, Nishiyama, Akira
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034279/
https://ncbi.nlm.nih.gov/pubmed/21243738
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