Alternative Polyadenylation of Adeno-Associated Virus Type 5 RNA within an Internal Intron Is Governed by both a Downstream Element within the Intron 3′ Splice Acceptor and an Element Upstream of the P41 Initiation Site

Adeno-associated virus type 5 (AAV5) has a linear, single-stranded DNA genome of ca. 5 kb and an overlapping transcription profile featuring multiple promoters and a single intron in the center of the genome. Unlike the situation for the prototype AAV2, AAV5 RNAs transcribed from upstream promoters...

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Bibliographic Details
Main Authors: Qiu, Jianming, Nayak, Ramnath, Pintel, David J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC303416/
https://ncbi.nlm.nih.gov/pubmed/14671090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.83-93.2004
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