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Metformin Inhibits Isoproterenol-induced Cardiac Hypertrophy in Mice

The present study examined whether metformin treatment prevents isoporterenol-induced cardiac hypertrophy in mice. Chronic subcutaneous infusion of isoproterenol (15 mg/kg/24 h) for 1 week using an osmotic minipump induced cardiac hypertrophy measured by the heart-to-body weight ratio and left ventr...

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Hlavní autoři: Cha, Hye-Na, Choi, Jung Hyun, Kim, Yong-Woon, Kim, Jong-Yeon, Ahn, Myun-Whan, Park, So-Young
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Physiological Society and The Korean Society of Pharmacology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034117/
https://ncbi.nlm.nih.gov/pubmed/21311678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2010.14.6.377
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