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Selection of Functional 5′ cis-Acting Elements Promoting Efficient Sindbis Virus Genome Replication

The 5′ portion of the Sindbis virus (SIN) genome RNA is multifunctional. Besides initiating translation of the nonstructural polyprotein, RNA elements in the 5′ 200 bases of the SIN genome RNA, or its complement at the 3′ end of the negative-strand intermediate, play key roles in the synthesis of bo...

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Detalhes bibliográficos
Main Authors: Gorchakov, Rodion, Hardy, Richard, Rice, Charles M., Frolov, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303405/
https://ncbi.nlm.nih.gov/pubmed/14671088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.61-75.2004
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