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Selection of Functional 5′ cis-Acting Elements Promoting Efficient Sindbis Virus Genome Replication

The 5′ portion of the Sindbis virus (SIN) genome RNA is multifunctional. Besides initiating translation of the nonstructural polyprotein, RNA elements in the 5′ 200 bases of the SIN genome RNA, or its complement at the 3′ end of the negative-strand intermediate, play key roles in the synthesis of bo...

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Autors principals: Gorchakov, Rodion, Hardy, Richard, Rice, Charles M., Frolov, Ilya
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC303405/
https://ncbi.nlm.nih.gov/pubmed/14671088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.61-75.2004
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