Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages

TAL1/SCL is a master regulator of haematopoiesis whose expression promotes opposite outcomes depending on the cell type: differentiation in the erythroid lineage or oncogenesis in the T-cell lineage. Here, we used a combination of ChIP sequencing and gene expression profiling to compare the function...

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Detalhes bibliográficos
Main Authors: Palii, Carmen G, Perez-Iratxeta, Carolina, Yao, Zizhen, Cao, Yi, Dai, Fengtao, Davison, Jerry, Atkins, Harold, Allan, David, Dilworth, F Jeffrey, Gentleman, Robert, Tapscott, Stephen J, Brand, Marjorie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034015/
https://ncbi.nlm.nih.gov/pubmed/21179004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.342
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