CRTC1 Expression during Normal and Abnormal Salivary Gland Development Supports a Precursor Cell Origin for Mucoepidermoid Cancer

Dysregulation of the transcription factor CRTC1 by a t(11;19) chromosomal rearrangement mediates the formation of mucoepidermoid salivary gland carcinoma (MEC). Although the Crtc1 promoter is consistently active in fusion-positive MEC and low levels of Crtc1 transcripts have been reported in normal...

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Hlavní autoři: Jaskoll, Tina, Htet, Khine, Abichaker, George, Kaye, Frederic J, Melnick, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033996/
https://ncbi.nlm.nih.gov/pubmed/20837164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gep.2010.09.003
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