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CRTC1 Expression during Normal and Abnormal Salivary Gland Development Supports a Precursor Cell Origin for Mucoepidermoid Cancer
Dysregulation of the transcription factor CRTC1 by a t(11;19) chromosomal rearrangement mediates the formation of mucoepidermoid salivary gland carcinoma (MEC). Although the Crtc1 promoter is consistently active in fusion-positive MEC and low levels of Crtc1 transcripts have been reported in normal...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033996/ https://ncbi.nlm.nih.gov/pubmed/20837164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gep.2010.09.003 |
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