Inhibition of S-Phase Cyclin-Dependent Kinase Activity Blocks Expression of Epstein-Barr Virus Immediate-Early and Early Genes, Preventing Viral Lytic Replication

The induction of lytic replication of the Epstein-Barr virus (EBV) completely arrests cell cycle progression, in spite of elevation of S-phase cyclin-dependent kinase (CDK) activity, thereby causing accumulation of hyperphosphorylated forms of retinoblastoma (Rb) protein (A. Kudoh, M. Fujita, T. Kiy...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kudoh, Ayumi, Daikoku, Tohru, Sugaya, Yutaka, Isomura, Hiroki, Fujita, Masatoshi, Kiyono, Tohru, Nishiyama, Yukihiro, Tsurumi, Tatsuya
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303396/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14671092/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.1.104-115.2004
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