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Herpes Simplex Virus Type 1 Immediate-Early Gene Expression Is Required for the Induction of Apoptosis in Human Epithelial HEp-2 Cells

Wild-type herpes simplex virus type 1 (HSV-1) induces apoptosis in human epithelial HEp-2 cells, but infected cell proteins produced later in infection block the process from killing the cells. Thus, HSV-1 infection in the presence of the translational inhibitor cycloheximide (CHX) results in apopto...

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Vydáno v:J Virol
Hlavní autoři: Sanfilippo, Christine M., Chirimuuta, Fungai N. W., Blaho, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303390/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14671104/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.1.224-239.2004
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