An External Loop Region of Domain III of Dengue Virus Type 2 Envelope Protein Is Involved in Serotype-Specific Binding to Mosquito but Not Mammalian Cells

Dengue virus (DV) is a flavivirus and infects mammalian cells through mosquito vectors. This study investigates the roles of domain III of DV type 2 envelope protein (EIII) in DV binding to the host cell. Recombinant EIII interferes with DV infection to BHK21 and C6/36 cells by blocking dengue virio...

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Bibliographische Detailangaben
Hauptverfasser: Hung, Jan-Jong, Hsieh, Meng-Ti, Young, Ming-Jer, Kao, Chuan-Liang, King, Chwan-Chuen, Chang, Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC303388/
https://ncbi.nlm.nih.gov/pubmed/14671119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.378-388.2004
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