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Efficacy of Glutathione in Ameliorating Sulfur Mustard Analog-Induced Toxicity in Cultured Skin Epidermal Cells and in SKH-1 Mouse Skin In Vivo

Exposure to chemical warfare agent sulfur mustard (HD) is reported to cause GSH depletion, which plays an important role in HD-linked oxidative stress and skin injury. Using the HD analog 2-chloroethyl ethyl sulfide (CEES), we evaluated the role of GSH and its efficacy in ameliorating CEES-caused sk...

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Detalhes bibliográficos
Main Authors: Tewari-Singh, Neera, Agarwal, Chapla, Huang, Jie, Day, Brian J., White, Carl W., Agarwal, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033716/
https://ncbi.nlm.nih.gov/pubmed/20974699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.173708
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