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Initial Development and Validation of a Novel Extraction Method for Quantitative Mining of the Formalin-Fixed, Paraffin-Embedded Tissue Proteome for Biomarker Investigations
[Image: see text] Annotated formalin-fixed, paraffin-embedded (FFPE) tissue archives constitute a valuable resource for retrospective biomarker discovery. However, proteomic exploration of archival tissue is impeded by extensive formalin-induced covalent cross-linking. Robust methodology enabling pr...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2010
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033703/ https://ncbi.nlm.nih.gov/pubmed/21117664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr100812d |
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