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TMEM16A(a)/anoctamin-1 Shares a Homodimeric Architecture with CLC Chloride Channels

TMEM16A/anoctamin-1 has been identified as a protein with the classic properties of a Ca(2+)-activated chloride channel. Here, we used blue native polyacrylamide gel electrophoresis (BN-PAGE) and chemical cross-linking to assess the quaternary structure of the mouse TMEM16A(a) and TMEM16A(ac) splice...

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Autors principals: Fallah, Ghada, Römer, Thomas, Detro-Dassen, Silvia, Braam, Ursula, Markwardt, Fritz, Schmalzing, Günther
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033684/
https://ncbi.nlm.nih.gov/pubmed/20974900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.004697
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