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Nuclear Import of Histone Deacetylase 5 by Requisite Nuclear Localization Signal Phosphorylation
Histone deacetylase 5 (HDAC5), a class IIa deacetylase, is a prominent regulator of cellular and epigenetic processes that underlie the progression of human disease, ranging from cardiac hypertrophy to cancer. Although it is established that phosphorylation mediates 14–3-3 protein binding and provid...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Biochemistry and Molecular Biology
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033682/ https://ncbi.nlm.nih.gov/pubmed/21081666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.004317 |
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