Nuclear Import of Histone Deacetylase 5 by Requisite Nuclear Localization Signal Phosphorylation

Histone deacetylase 5 (HDAC5), a class IIa deacetylase, is a prominent regulator of cellular and epigenetic processes that underlie the progression of human disease, ranging from cardiac hypertrophy to cancer. Although it is established that phosphorylation mediates 14–3-3 protein binding and provid...

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Bibliographic Details
Main Authors: Greco, Todd M., Yu, Fang, Guise, Amanda J., Cristea, Ileana M.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2011
Subjects:
Regular Issue
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033682/
https://ncbi.nlm.nih.gov/pubmed/21081666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.004317
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