Mutations in the Gal83 Glycogen-Binding Domain Activate the Snf1/Gal83 Kinase Pathway by a Glycogen-Independent Mechanism

The yeast Snf1 kinase and its mammalian ortholog, AMP-activated protein kinase (AMPK), regulate responses to metabolic stress. Previous studies identified a glycogen-binding domain in the AMPK β1 subunit, and the sequence is conserved in the Snf1 kinase β subunits Gal83 and Sip2. Here we use genetic...

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Detalhes bibliográficos
Main Authors: Wiatrowski, Heather A., van Denderen, Bryce J. W., Berkey, Cristin D., Kemp, Bruce E., Stapleton, David, Carlson, Marian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303368/
https://ncbi.nlm.nih.gov/pubmed/14673168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.352-361.2004
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