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Roles of the Glycogen-binding Domain and Snf4 in Glucose Inhibition of SNF1 Protein Kinase

The SNF1/AMP-activated protein kinase (AMPK) family is required for adaptation to metabolic stress and energy homeostasis. The γ subunit of AMPK binds AMP and ATP, and mutations that affect binding cause human disease. We have here addressed the role of the Snf4 (γ) subunit in regulating SNF1 protei...

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Detalhes bibliográficos
Main Authors: Momcilovic, Milica, Iram, Surtaj H., Liu, Yang, Carlson, Marian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443652/
https://ncbi.nlm.nih.gov/pubmed/18474591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803624200
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