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Role for BRG1 in Cell Cycle Control and Tumor Suppression

Human BRG1, a subunit of the Swi/Snf chromatin remodeling apparatus, has been implicated in regulation of cellular proliferation and is a candidate tumor suppressor. Reintroduction of BRG1 into a breast tumor cell line, ALAB, carrying a defined mutation in the BRG1 gene, induced growth arrest. Gene...

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Detalhes bibliográficos
Main Authors: Hendricks, Kristin B., Shanahan, Frances, Lees, Emma
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303366/
https://ncbi.nlm.nih.gov/pubmed/14673169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.362-376.2004
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