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WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ
The transcriptional co-activators YAP and TAZ are downstream targets inhibited by the Hippo tumor suppressor pathway. YAP and TAZ both possess WW domains, which are important protein–protein interaction modules that mediate interaction with proline-rich motifs, most commonly PPXY. The WW domains of...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033532/ https://ncbi.nlm.nih.gov/pubmed/20972459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.438 |
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