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Remarkable Levels of Enantioswitching in Catalytic Asymmetric Hydroboration

[Image: see text] TADDOL-derived phosphites and phosphoramidites are effective ligands for rhodium-catalyzed asymmetric hydroborations of β,γ-unsaturated amides, achieving up to 99% ee. However, the sense of stereoinduction, R or S, is surprisingly dependent on rather subtle features of the ligand....

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Detalhes bibliográficos
Main Authors: Smith, Sean M., Takacs, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033434/
https://ncbi.nlm.nih.gov/pubmed/20863120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101932q
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