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Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome

Internal ribosome entry site (IRES) RNAs are elements of viral or cellular mRNAs that bypass steps of canonical eukaryotic cap-dependent translation initiation. Understanding of the structural basis of IRES mechanisms is limited, partially due to a lack of high-resolution structures of IRES RNAs bou...

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Autori principali: Zhu, Jianyu, Korostelev, Andrei, Costantino, David A., Donohue, John P., Noller, Harry F., Kieft, Jeffrey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033271/
https://ncbi.nlm.nih.gov/pubmed/21245352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018582108
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