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Crystal structure of the 70S ribosome bound with the Q253P mutant form of release factor RF2

Bacterial translation termination is mediated by release factors RF1 and RF2, which recognize stop codons and catalyze hydrolysis of the peptidyl-tRNA ester bond. The catalytic mechanism has been debated. We proposed that the backbone amide NH group, rather than the side chain, of the glutamine of t...

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Detalhes bibliográficos
Main Authors: Santos, Natalia, Zhu, Jianyu, Donohue, John Paul, Korostelev, Andrei A., Noller, Harry F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923520/
https://ncbi.nlm.nih.gov/pubmed/23769667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.04.028
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