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Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells

Both Foxp3(+) regulatory T cells (Tregs) and antigen-expanded Foxp3(−) Tregs play an important role in regulating immune responses as well as in preventing autoimmune diseases and graft rejection. Molecular mechanisms modulating Treg function remain largely unclear, however. We report here on the ex...

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Detalhes bibliográficos
Main Authors: Qin, Hanjun, Wang, Zunde, Du, Weiting, Lee, Wen-Hui, Wu, Xiwei, Riggs, Arthur D., Liu, Chih-Pin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033262/
https://ncbi.nlm.nih.gov/pubmed/21245333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019082108
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