Inactivation of E2F3 results in centrosome amplification

The E2F family of transcription factors is critical for the control of cell cycle progression. We now show that the specific inactivation of E2F3 in mouse embryo fibroblasts (MEFs) results in a disruption of the centrosome duplication cycle. Loss of E2F3, but not E2F1, E2F2, E2F4, or E2F5 results in...

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Bibliographic Details
Main Authors:	Saavedra, Harold I., Maiti, Baidehi, Timmers, Cynthia, Altura, Rachel, Tokuyama, Yukari, Fukasawa, Kenji, Leone, Gustavo
Format:	Artigo
Language:	Inglês
Published:	2003
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3033013/ https://ncbi.nlm.nih.gov/pubmed/12726860
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Inactivation of E2F3 results in centrosome amplification

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