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E2f1, E2f2, and E2f3 Control E2F Target Expression and Cellular Proliferation via a p53-Dependent Negative Feedback Loop

E2F-mediated control of gene expression is believed to have an essential role in the control of cellular proliferation. Using a conditional gene-targeting approach, we show that the targeted disruption of the entire E2F activator subclass composed of E2f1, E2f2, and E2f3 in mouse embryonic fibroblas...

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Bibliografische gegevens
Hoofdauteurs: Timmers, Cynthia, Sharma, Nidhi, Opavsky, Rene, Maiti, Baidehi, Wu, Lizhao, Wu, Juan, Orringer, Daniel, Trikha, Prashant, Saavedra, Harold I., Leone, Gustavo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800646/
https://ncbi.nlm.nih.gov/pubmed/17167174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02147-05
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